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Propylene glycol, the main component of e-cigarette, can inhibit oral bacteria and inflammation

2022/03/02|Knowledge

How e-cigarettes affect oral health has always been a concern of users. According to a research paper recently released by the American Chemical Society, propylene glycol, the main component of electronic smog solution, can inhibit oral bacteria and induced inflammation. Smokers switching to electronic cigarettes may effectively reduce the risk of oral diseases such as oral cancer.

American Chemical Society: propylene glycol, the main component of e-cigarette, can inhibit oral bacteria and inflammation, or reduce the risk of oral cancer

Picture: the paper is published in the authoritative journal Toxicological Chemistry Research. The picture is a screenshot of the official website of the American Chemical Society

The American Chemical Society is one of the world's largest scientific organizations, authorized by the U.S. Congress, with more than 150000 members in 140 countries. Propylene glycol is mainly used to enhance the stability of electronic smog solution. Researchers found that propylene glycol has certain antibacterial effect through a group of animal experiments.

Research shows that propylene glycol with a concentration of 0.5ppm can quickly sterilize Streptococcus pneumoniae, influenza virus and other microorganisms in a confined space. With the increasing concentration, propylene glycol can also inhibit the growth of Escherichia coli, Streptococcus mutans and other pathogenic bacteria. Among them, Streptococcus mutans is an important factor leading to tooth decay, and Escherichia coli can cause gastrointestinal infection.

In order to further explore the impact of e-cigarette on human oral environment, 30 smokers and 30 e-cigarette users were selected, and the method of detecting human oral cell AP sites (purine pyrimidine free sites) was adopted for the first time - DNA damage will form AP sites. The higher the level of AP sites, the more serious the DNA damage, and the more likely it will lead to gene mutation and cancer.

Effect of electronic cigarette on oral cavity

Picture: quantitative study of AP sites by liquid chromatography

The results showed that the level of AP site in oral cell DNA of e-cigarette users was 3.3/107nts, which was much lower than that of smokers. The gap is particularly obvious in the 30-50 age group. The AP locus level of e-cigarette users in this group (3.0 / 107nts) is twice lower than that of smokers (6.0 / 107nts).

Does this mean that smokers will improve their oral environment after switching to electronic cigarettes? The world-famous SCI Journal Journal of dental research published relevant research papers in 2021. The results showed that after smokers with oral diseases switched to electronic cigarettes, their periodontal environment would be improved whether dentists provided treatment services or not.

Electronic cigarette and oral health

Figure: the research paper "e-cigarette and oral health" published on the official website of the Journal of dental research was jointly carried out by dental experts from many universities, such as the University of Newcastle in the UK and the University of California in the United States

"There are more than 700 kinds of bacteria in the mouth, and the vast majority of patients with oral diseases are smokers." British dental expert R. Holliday said: "the comparative study of e-cigarettes and cigarettes is very useful for us. I hope dentists can put aside their prejudice and learn more about the positive impact of e-cigarettes on the oral health of sick smokers."

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